USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B‐cell lymphoma

The mitotic spindle assembly checkpoint (SAC) maintains genome stability and marks an important target for antineoplastic therapies. However, it has remained unclear how cells execute cell fate decisions under conditions of SAC‐induced mitotic arrest. Here, we identify USP9X as the mitotic deubiquit...

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Bibliografiska uppgifter
I publikationen:EMBO Mol Med
Huvudupphovsmän: Engel, Katharina, Rudelius, Martina, Slawska, Jolanta, Jacobs, Laura, Ahangarian Abhari, Behnaz, Altmann, Bettina, Kurutz, Julia, Rathakrishnan, Abirami, Fernández‐Sáiz, Vanesa, Brunner, Andrä, Targosz, Bianca‐Sabrina, Loewecke, Felicia, Gloeckner, Christian Johannes, Ueffing, Marius, Fulda, Simone, Pfreundschuh, Michael, Trümper, Lorenz, Klapper, Wolfram, Keller, Ulrich, Jost, Philipp J, Rosenwald, Andreas, Peschel, Christian, Bassermann, Florian
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
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Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967940/
https://ncbi.nlm.nih.gov/pubmed/27317434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201506047
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