USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B‐cell lymphoma

The mitotic spindle assembly checkpoint (SAC) maintains genome stability and marks an important target for antineoplastic therapies. However, it has remained unclear how cells execute cell fate decisions under conditions of SAC‐induced mitotic arrest. Here, we identify USP9X as the mitotic deubiquit...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Engel, Katharina, Rudelius, Martina, Slawska, Jolanta, Jacobs, Laura, Ahangarian Abhari, Behnaz, Altmann, Bettina, Kurutz, Julia, Rathakrishnan, Abirami, Fernández‐Sáiz, Vanesa, Brunner, Andrä, Targosz, Bianca‐Sabrina, Loewecke, Felicia, Gloeckner, Christian Johannes, Ueffing, Marius, Fulda, Simone, Pfreundschuh, Michael, Trümper, Lorenz, Klapper, Wolfram, Keller, Ulrich, Jost, Philipp J, Rosenwald, Andreas, Peschel, Christian, Bassermann, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967940/
https://ncbi.nlm.nih.gov/pubmed/27317434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201506047
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