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Small-Molecule XIAP Inhibitors Enhance γ-Irradiation-Induced Apoptosis in Glioblastoma

Because evasion of apoptosis can cause radioresistance of glioblastoma, there is a need to design rational strategies that counter apoptosis resistance. In the present study, we investigated the potential of targeting the antiapoptotic protein XIAP for the radiosensitization of glioblastoma. Here, w...

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Detalhes bibliográficos
Main Authors: Vellanki, Sri Hari Krishna, Grabrucker, Andreas, Liebau, Stefan, Proepper, Christian, Eramo, Adriana, Braun, Veit, Boeckers, Tobias, Debatin, Klaus-Michael, Fulda, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713593/
https://ncbi.nlm.nih.gov/pubmed/19649204
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