載入...

The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific

The apolipoprotein (apo) E4 isoform is the strongest risk factor for late-onset Alzheimer’s disease (AD). ApoE4 is more susceptible to proteolysis than apoE2 and apoE3 isoforms and carboxyl-terminal truncated apoE4 forms have been found in AD patients’ brain. We have previously shown that a specific...

全面介紹

Na minha lista:
書目詳細資料
發表在:Sci Rep
Main Authors: Dafnis, Ioannis, Argyri, Letta, Sagnou, Marina, Tzinia, Athina, Tsilibary, Effie C., Stratikos, Efstratios, Chroni, Angeliki
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967930/
https://ncbi.nlm.nih.gov/pubmed/27476701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30654
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!