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Heat shock factor 1 induces crystallin-αB to protect against cisplatin nephrotoxicity

Cisplatin, a wildly used chemotherapy drug, induces nephrotoxicity that is characterized by renal tubular cell apoptosis. In response to toxicity, tubular cells can activate cytoprotective mechanisms, such as the heat shock response. However, the role and regulation of the heat shock response in cis...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Renal Physiol
Asıl Yazarlar: Lou, Qiang, Hu, Yanzhong, Ma, Yuanfang, Dong, Zheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967155/
https://ncbi.nlm.nih.gov/pubmed/27194715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00201.2016
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