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Heat shock factor 1 induces crystallin-αB to protect against cisplatin nephrotoxicity
Cisplatin, a wildly used chemotherapy drug, induces nephrotoxicity that is characterized by renal tubular cell apoptosis. In response to toxicity, tubular cells can activate cytoprotective mechanisms, such as the heat shock response. However, the role and regulation of the heat shock response in cis...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4967155/ https://ncbi.nlm.nih.gov/pubmed/27194715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00201.2016 |
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