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Heat shock factor 1 induces crystallin-αB to protect against cisplatin nephrotoxicity

Cisplatin, a wildly used chemotherapy drug, induces nephrotoxicity that is characterized by renal tubular cell apoptosis. In response to toxicity, tubular cells can activate cytoprotective mechanisms, such as the heat shock response. However, the role and regulation of the heat shock response in cis...

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Pubblicato in:Am J Physiol Renal Physiol
Autori principali: Lou, Qiang, Hu, Yanzhong, Ma, Yuanfang, Dong, Zheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967155/
https://ncbi.nlm.nih.gov/pubmed/27194715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00201.2016
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