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Heat shock factor 1 induces crystallin-αB to protect against cisplatin nephrotoxicity

Cisplatin, a wildly used chemotherapy drug, induces nephrotoxicity that is characterized by renal tubular cell apoptosis. In response to toxicity, tubular cells can activate cytoprotective mechanisms, such as the heat shock response. However, the role and regulation of the heat shock response in cis...

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Detalles Bibliográficos
Publicado en:Am J Physiol Renal Physiol
Main Authors: Lou, Qiang, Hu, Yanzhong, Ma, Yuanfang, Dong, Zheng
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967155/
https://ncbi.nlm.nih.gov/pubmed/27194715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00201.2016
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