Pharmacokinetics and pharmacodynamics of ch14.18/CHO in relapsed/refractory high-risk neuroblastoma patients treated by long-term infusion in combination with IL-2

Ch14.18 manufactured in Chinese hamster ovary (CHO) cells is currently being evaluated in clinical trials. Short-term infusion (STI) (8–20 h/day; 4–5 days) of 100 mg/m2 ch14.18/CHO (dinutiximab β) per cycle in combination with cytokines is standard treatment of neuroblastoma (NB) patients. As pain i...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Siebert, Nikolai, Eger, Christin, Seidel, Diana, Jüttner, Madlen, Zumpe, Maxi, Wegner, Danilo, Kietz, Silke, Ehlert, Karoline, Veal, Gareth J., Siegmund, Werner, Weiss, Michael, Loibner, Hans, Ladenstein, Ruth, Lode, Holger N.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966854/
https://ncbi.nlm.nih.gov/pubmed/26785755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1130196
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