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Computational tool for the early screening of monoclonal antibodies for their viscosities

Highly concentrated antibody solutions often exhibit high viscosities, which present a number of challenges for antibody-drug development, manufacturing and administration. The antibody sequence is a key determinant for high viscosity of highly concentrated solutions; therefore, a sequence- or struc...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Agrawal, Neeraj J, Helk, Bernhard, Kumar, Sandeep, Mody, Neil, Sathish, Hasige A., Samra, Hardeep S., Buck, Patrick M, Li, Li, Trout, Bernhardt L
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966561/
https://ncbi.nlm.nih.gov/pubmed/26399600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1099773
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