Immunodiagnosis of platelet activation in immune thrombocytopenia through scFv antibodies cognate to activated IIb3 integrins

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by low platelet count and presence of IgG autoantibodies to platelet surface glycoproteins, such as [Formula: see text] IIbβ3 and GPIb/IX. Our previous work has shown that platelets in ITP patients exist in an activated s...

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Bibliographic Details
Published in:MAbs
Main Authors: Bhoria, Preeti, Varma, Neelam, Malhotra, Pankaj, Varma, Subhash, Luthra-Guptasarma, Manni
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966486/
https://ncbi.nlm.nih.gov/pubmed/26301697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1075681
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