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Immunodiagnosis of platelet activation in immune thrombocytopenia through scFv antibodies cognate to activated IIb3 integrins

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by low platelet count and presence of IgG autoantibodies to platelet surface glycoproteins, such as [Formula: see text] IIbβ3 and GPIb/IX. Our previous work has shown that platelets in ITP patients exist in an activated s...

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Bibliografiske detaljer
Udgivet i:MAbs
Main Authors: Bhoria, Preeti, Varma, Neelam, Malhotra, Pankaj, Varma, Subhash, Luthra-Guptasarma, Manni
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966486/
https://ncbi.nlm.nih.gov/pubmed/26301697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1075681
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