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An Unprecedented Glycation Reactivity of a Quorum-Sensing Signaling Molecule
We report that the (4S)-4,5-dihydroxy-2,3-pentanedione (DPD) can undergo a previously undocumented non-enzymatic glycation reaction. Incubation of DPD with viral DNA or the antibiotic gramicidin S resulted in significant biochemical alterations. A protein labeling method was consequently developed t...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4965832/ https://ncbi.nlm.nih.gov/pubmed/26890076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201511911 |
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