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Dissecting AI-2-mediated quorum sensing through C5-analogue synthesis and biochemical analysis

Autoinducer-2 (AI-2)-mediated quorum sensing (QS) is utilised for both intra- and inter-species communication by a wide variety of bacteria. An understanding of the mechanism of this communication has the potential to elucidate new targets for antibacterial therapeutics. Herein, we report the synthe...

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Detalhes bibliográficos
Publicado no:Tetrahedron
Main Authors: Collins, Karen C., Tsuchikama, Kyoji, Lowery, Colin A., Zhu, Jie, Janda, Kim D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915392/
https://ncbi.nlm.nih.gov/pubmed/27340303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2015.08.063
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