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Mechanistic insights into the LsrK kinase required for autoinducer-2 quorum sensing activation
In enteric bacteria, the kinase LsrK catalyzes the phosphorylation of the C5-hydroxyl group in the linear form of 4,5-dihydroxy-2,3-pentanedione (DPD), the precursor of the type II bacterial quorum sensing molecule (AI-2). This phosphorylation is required for AI-2 sequestration in the cytoplasm and...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736694/ https://ncbi.nlm.nih.gov/pubmed/23672516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4024989 |
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