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Targeting Quorum Sensing: High-Throughput Screening to Identify Novel LsrK Inhibitors

Since quorum sensing (QS) is linked to the establishment of bacterial infection, its inactivation represents one of the newest strategies to fight bacterial pathogens. LsrK is a kinase playing a key role in the processing of autoinducer-2 (AI-2), a quorum-sensing mediator in gut enteric bacteria. In...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Gatta, Viviana, Ilina, Polina, Porter, Alison, McElroy, Stuart, Tammela, Päivi
格式: Artigo
語言:Inglês
出版: MDPI 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627609/
https://ncbi.nlm.nih.gov/pubmed/31242708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20123112
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