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Targeting Quorum Sensing: High-Throughput Screening to Identify Novel LsrK Inhibitors

Since quorum sensing (QS) is linked to the establishment of bacterial infection, its inactivation represents one of the newest strategies to fight bacterial pathogens. LsrK is a kinase playing a key role in the processing of autoinducer-2 (AI-2), a quorum-sensing mediator in gut enteric bacteria. In...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gatta, Viviana, Ilina, Polina, Porter, Alison, McElroy, Stuart, Tammela, Päivi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627609/
https://ncbi.nlm.nih.gov/pubmed/31242708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20123112
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