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Targeting Quorum Sensing: High-Throughput Screening to Identify Novel LsrK Inhibitors
Since quorum sensing (QS) is linked to the establishment of bacterial infection, its inactivation represents one of the newest strategies to fight bacterial pathogens. LsrK is a kinase playing a key role in the processing of autoinducer-2 (AI-2), a quorum-sensing mediator in gut enteric bacteria. In...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6627609/ https://ncbi.nlm.nih.gov/pubmed/31242708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20123112 |
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