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Targeting Quorum Sensing: High-Throughput Screening to Identify Novel LsrK Inhibitors

Since quorum sensing (QS) is linked to the establishment of bacterial infection, its inactivation represents one of the newest strategies to fight bacterial pathogens. LsrK is a kinase playing a key role in the processing of autoinducer-2 (AI-2), a quorum-sensing mediator in gut enteric bacteria. In...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Gatta, Viviana, Ilina, Polina, Porter, Alison, McElroy, Stuart, Tammela, Päivi
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627609/
https://ncbi.nlm.nih.gov/pubmed/31242708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20123112
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