Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia

BACKGROUND: Methylation changes are frequent in cancers, but understanding how hyper- and hypomethylated region changes coordinate, associate with genomic features, and affect gene expression is needed to better understand their biological significance. The functional significance of hypermethylatio...

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Bibliographic Details
Published in:Hum Genomics
Main Authors: Kushwaha, Garima, Dozmorov, Mikhail, Wren, Jonathan D., Qiu, Jing, Shi, Huidong, Xu, Dong
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965721/
https://ncbi.nlm.nih.gov/pubmed/27461342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-016-0071-5
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