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Coordinate hypermethylation at specific genes in prostate carcinoma precedes LINE-1 hypomethylation
In prostate carcinoma (PCa) increased DNA methylation (‘hypermethylation’) occurs at specific genes such as GSTP1. Nevertheless, overall methylation can be decreased (‘hypomethylation’) because methylation of repetitive sequences like LINE-1 retrotransposons is diminished. We analysed DNA from 113 P...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409889/ https://ncbi.nlm.nih.gov/pubmed/15292941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602030 |
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