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High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer

Changes in DNA methylation patterns are an important characteristic of human cancer. Tumors have reduced levels of genomic DNA methylation and contain hypermethylated CpG islands, but the full extent and sequence context of DNA hypomethylation and hypermethylation is unknown. Here, we used methylate...

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Detalhes bibliográficos
Main Authors: Rauch, Tibor A., Zhong, Xueyan, Wu, Xiwei, Wang, Melody, Kernstine, Kemp H., Wang, Zunde, Riggs, Arthur D., Pfeifer, Gerd P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224196/
https://ncbi.nlm.nih.gov/pubmed/18162535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710735105
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