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The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells

Small cell lung cancer (SCLC) is a disease characterized by aggressive clinical behavior and lack of effective therapy. Due to its tendency for early dissemination, only a third of patients have limited-stage disease at the time of diagnosis. SCLC is thought to derive from pulmonary neuroendocrine c...

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Autors principals: Kalari, Satish, Jung, Marc, Kernstine, Kemp H., Takahashi, Takashi, Pfeifer, Gerd P.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625455/
https://ncbi.nlm.nih.gov/pubmed/22907430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.362
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