miR-30 Family Controls Proliferation and Differentiation of Intestinal Epithelial Cell Models by Directing a Broad Gene Expression Program That Includes SOX9 and the Ubiquitin Ligase Pathway

Proliferation and differentiation of intestinal epithelial cells (IECs) occur in part through precise regulation of key transcription factors, such as SOX9. MicroRNAs (miRNAs) have emerged as prominent fine-tuners of transcription factor expression and activity. We hypothesized that miRNAs, in part...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Peck, Bailey C. E., Sincavage, John, Feinstein, Sydney, Mah, Amanda T., Simmons, James G., Lund, P. Kay, Sethupathy, Praveen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965549/
https://ncbi.nlm.nih.gov/pubmed/27261459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.733733
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