miR-30 Family Controls Proliferation and Differentiation of Intestinal Epithelial Cell Models by Directing a Broad Gene Expression Program That Includes SOX9 and the Ubiquitin Ligase Pathway

Proliferation and differentiation of intestinal epithelial cells (IECs) occur in part through precise regulation of key transcription factors, such as SOX9. MicroRNAs (miRNAs) have emerged as prominent fine-tuners of transcription factor expression and activity. We hypothesized that miRNAs, in part...

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Vydáno v:J Biol Chem
Hlavní autoři: Peck, Bailey C. E., Sincavage, John, Feinstein, Sydney, Mah, Amanda T., Simmons, James G., Lund, P. Kay, Sethupathy, Praveen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965549/
https://ncbi.nlm.nih.gov/pubmed/27261459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.733733
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