miR-30 Family Controls Proliferation and Differentiation of Intestinal Epithelial Cell Models by Directing a Broad Gene Expression Program That Includes SOX9 and the Ubiquitin Ligase Pathway

Proliferation and differentiation of intestinal epithelial cells (IECs) occur in part through precise regulation of key transcription factors, such as SOX9. MicroRNAs (miRNAs) have emerged as prominent fine-tuners of transcription factor expression and activity. We hypothesized that miRNAs, in part...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Peck, Bailey C. E., Sincavage, John, Feinstein, Sydney, Mah, Amanda T., Simmons, James G., Lund, P. Kay, Sethupathy, Praveen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965549/
https://ncbi.nlm.nih.gov/pubmed/27261459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.733733
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