C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis

The CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP), a major transcriptional regulator of endoplasmic reticulum (ER) stress-mediated apoptosis, is implicated in lipotoxicity-induced ER stress and hepatocyte apoptosis in non-alcoholic fatty liver disease (NAFLD). We have previously d...

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Udgivet i:Lab Invest
Main Authors: Rahman, Khalidur, Liu, Yunshan, Kumar, Pradeep, Smith, Tekla, Thorn, Natalie E., Farris, Alton B., Anania, Frank A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965279/
https://ncbi.nlm.nih.gov/pubmed/27239734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2016.61
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