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Western diet-induced increase in colonic bile acids compromises epithelial barrier in nonalcoholic steatohepatitis

There is compelling evidence implicating intestinal permeability in the pathogenesis of nonalcoholic steatohepatitis (NASH), but the underlying mechanisms remain poorly understood. Here we examined the role of bile acids (BA) in western diet (WD)-induced loss of colonic epithelial barrier (CEB) func...

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Библиографические подробности
Опубликовано в: :FASEB J
Главные авторы: Gupta, Biki, Liu, Yunshan, Chopyk, Daniel M., Rai, Ravi P., Desai, Chirayu, Kumar, Pradeep, Farris, Alton B., Nusrat, Asma, Parkos, Charles A., Anania, Frank A., Raeman, Reben
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831197/
https://ncbi.nlm.nih.gov/pubmed/32275114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902687R
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