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An Effective Top-down LC/MS+ Method for Assessing Actin Isoforms as a Potential Cardiac Disease Marker

Actin is the major component of the cytoskeleton playing an essential role in the structure and motility of both muscle and non-muscle cells. It is highly conserved and encoded by a multigene family. α-cardiac actin (αCAA) and α-skeletal actin (αSKA), encoded by two different genes, are the primary...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Chen, Yi-Chen, Ayaz-Guner, Serife, Peng, Ying, Lane, Nicole M., Locher, Matthew, Kohmoto, Takushi, Larsson, Lars, Moss, Richard L., Ge, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965275/
https://ncbi.nlm.nih.gov/pubmed/26189812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b01745
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