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Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons

Metformin is a widely prescribed drug used to treat type-2 diabetes, although recent studies show it has wide ranging effects to treat other diseases. Animal and retrospective human studies indicate that Metformin treatment is neuroprotective in Parkinson’s Disease (PD), although the neuroprotective...

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書誌詳細
出版年:PLoS One
主要な著者: Bayliss, Jacqueline A., Lemus, Moyra B., Santos, Vanessa V., Deo, Minh, Davies, Jeffrey S., Kemp, Bruce E., Elsworth, John D., Andrews, Zane B.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965122/
https://ncbi.nlm.nih.gov/pubmed/27467571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159381
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