Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease

Calorie restriction (CR) is neuroprotective in Parkinson's disease (PD) although the mechanisms are unknown. In this study we hypothesized that elevated ghrelin, a gut hormone with neuroprotective properties, during CR prevents neurodegeneration in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridin...

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Vydáno v:J Neurosci
Hlavní autoři: Bayliss, Jacqueline A., Lemus, Moyra B., Stark, Romana, Santos, Vanessa V., Thompson, Aiysha, Rees, Daniel J., Galic, Sandra, Elsworth, John D., Kemp, Bruce E., Davies, Jeffrey S., Andrews, Zane B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783502/
https://ncbi.nlm.nih.gov/pubmed/26961958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4373-15.2016
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