Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease

Calorie restriction (CR) is neuroprotective in Parkinson's disease (PD) although the mechanisms are unknown. In this study we hypothesized that elevated ghrelin, a gut hormone with neuroprotective properties, during CR prevents neurodegeneration in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridin...

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Publicado en:J Neurosci
Main Authors: Bayliss, Jacqueline A., Lemus, Moyra B., Stark, Romana, Santos, Vanessa V., Thompson, Aiysha, Rees, Daniel J., Galic, Sandra, Elsworth, John D., Kemp, Bruce E., Davies, Jeffrey S., Andrews, Zane B.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2016
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783502/
https://ncbi.nlm.nih.gov/pubmed/26961958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4373-15.2016
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