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Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease

Calorie restriction (CR) is neuroprotective in Parkinson's disease (PD) although the mechanisms are unknown. In this study we hypothesized that elevated ghrelin, a gut hormone with neuroprotective properties, during CR prevents neurodegeneration in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridin...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Bayliss, Jacqueline A., Lemus, Moyra B., Stark, Romana, Santos, Vanessa V., Thompson, Aiysha, Rees, Daniel J., Galic, Sandra, Elsworth, John D., Kemp, Bruce E., Davies, Jeffrey S., Andrews, Zane B.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783502/
https://ncbi.nlm.nih.gov/pubmed/26961958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4373-15.2016
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