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GPA protects the nigrostriatal dopamine system by enhancing mitochondrial function
Guanidinopropionic acid (GPA) increases AMPK activity, mitochondrial function and biogenesis in muscle and improves physiological function, for example during aging. Mitochondrial dysfunction is a major contributor to the pathogenesis of Parkinson’s disease. Here we tested whether GPA prevents neuro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623269/ https://ncbi.nlm.nih.gov/pubmed/21406233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.03.005 |
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