Competitive Fitness of Influenza B Viruses Possessing E119A and H274Y Neuraminidase Inhibitor Resistance–Associated Substitutions in Ferrets

Neuraminidase (NA) inhibitors (NAIs) are the only antiviral drugs recommended for influenza treatment and prophylaxis. Although NAI-resistant influenza B viruses that could pose a threat to public health have been reported in the field, their fitness is poorly understood. We evaluated in ferrets the...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Pascua, Philippe Noriel Q., Marathe, Bindumadhav M., Burnham, Andrew J., Vogel, Peter, Webby, Richard J., Webster, Robert G., Govorkova, Elena A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965113/
https://ncbi.nlm.nih.gov/pubmed/27466813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159847
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