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Truncated forms of the prion protein PrP demonstrate the need for complexity in prion structure

Self-propagation of aberrant protein folds is the defining characteristic of prions. Knowing the structural basis of self-propagation is essential to understanding prions and their related diseases. Prion rods are amyloid fibrils, but not all amyloids are prions. Prions have been remarkably intracta...

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Detalles Bibliográficos
Publicado en:Prion
Main Authors: Wan, William, Stöhr, Jan, Kendall, Amy, Stubbs, Gerald
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964866/
https://ncbi.nlm.nih.gov/pubmed/26325658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1084464
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