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PrP(ST), a Soluble, Protease Resistant and Truncated PrP Form Features in the Pathogenesis of a Genetic Prion Disease

While the conversion of PrP(C) into PrP(Sc) in the transmissible form of prion disease requires a preexisting PrP(Sc) seed, in genetic prion disease accumulation of disease related PrP could be associated with biochemical and metabolic modifications resulting from the designated PrP mutation. To inv...

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保存先:
書誌詳細
主要な著者: Friedman-Levi, Yael, Mizrahi, Michal, Frid, Kati, Binyamin, Orli, Gabizon, Ruth
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724911/
https://ncbi.nlm.nih.gov/pubmed/23922744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069583
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