Inhibition of leukemia cell proliferation by receptor-mediated uptake of c-myb antisense oligodeoxynucleotides.

Exposure of human leukemia HL-60 cells to an oligodeoxynucleotide complementary to an 18-base sequence (codons 2-7) of c-myb-encoded mRNA has previously been shown to result in inhibition of cell proliferation. Because HL-60 cells express high levels of transferrin receptor we adapted a DNA delivery...

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Hauptverfasser: Citro, G, Perrotti, D, Cucco, C, D'Agnano, I, Sacchi, A, Zupi, G, Calabretta, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC49639/
https://ncbi.nlm.nih.gov/pubmed/1495997
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