Inhibition of leukaemia cell proliferation by folic acid-polylysine-mediated introduction of c-myb antisense oligodeoxynucleotides into HL-60 cells.

The inhibitory effect of c-myb antisense oligodeoxynucleotides (ODNs) conjugated to folic acid (FA) on HL-60 cell proliferation was examined. Folic acid was covalently linked to a polylysine chain and purified by gel chromatography. Sterile FA-polylysine was complexed with c-myb sense and antisense....

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Bibliographic Details
Main Authors: Citro, G., Szczylik, C., Ginobbi, P., Zupi, G., Calabretta, B.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968841/
https://ncbi.nlm.nih.gov/pubmed/8123474
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