Effect of cisplatin and c-myb antisense phosphorothioate oligodeoxynucleotides combination on a human colon carcinoma cell line in vitro and in vivo.

We investigated the effect of c-myb antisense phosphorothioate oligodeoxynucleotides [(S)ODNs] and cisplatin (CDDP) combination on the human colon carcinoma cell line LoVo Dx both in vitro and in nude mice bearing LoVo Dx solid tumour. We show that antisense (S)ODN treatment decreases c-myb mRNA and...

Full description

Saved in:
Bibliographic Details
Main Authors: Del Bufalo, D., Cucco, C., Leonetti, C., Citro, G., D'Agnano, I., Benassi, M., Geiser, T., Zon, G., Calabretta, B., Zupi, G.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074645/
https://ncbi.nlm.nih.gov/pubmed/8695353
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items