Effect of cisplatin and c-myb antisense phosphorothioate oligodeoxynucleotides combination on a human colon carcinoma cell line in vitro and in vivo.

We investigated the effect of c-myb antisense phosphorothioate oligodeoxynucleotides [(S)ODNs] and cisplatin (CDDP) combination on the human colon carcinoma cell line LoVo Dx both in vitro and in nude mice bearing LoVo Dx solid tumour. We show that antisense (S)ODN treatment decreases c-myb mRNA and...

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Hauptverfasser: Del Bufalo, D., Cucco, C., Leonetti, C., Citro, G., D'Agnano, I., Benassi, M., Geiser, T., Zon, G., Calabretta, B., Zupi, G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1996
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074645/
https://ncbi.nlm.nih.gov/pubmed/8695353
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