Addition of Dexamethasone Alters the Bile Acid Composition by Inducing CYP8B1 in Primary Cultures of Human Hepatocytes

BACKGROUND: Primary human hepatocytes offer the best human in vitro model for studies on human liver cell metabolism. Investigators use a variety of different media supplements and matrix biocoatings and the type of culture system used may influence the outcome. OBJECTIVES: To optimize in vitro cond...

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Detalhes bibliográficos
Publicado no:J Clin Exp Hepatol
Main Authors: Mörk, Lisa-Mari, Strom, Stephen C., Mode, Agneta, Ellis, Ewa C.S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963319/
https://ncbi.nlm.nih.gov/pubmed/27493455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jceh.2016.01.007
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