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ATPase Class I Type 8B Member 1 and Protein Kinase C-ζ Induce the Expression of the Canalicular Bile Salt Export Pump in Human Hepatocytes

The exact molecular mechanism(s) of the disease that results from defects in the ATPase Class I Type 8B Member 1 gene remains controversial. Prior investigations of human ileum and in intestinal and ovarian cell lines have suggested that Familial Intrahepatic Cholestasis 1 (FIC1) activates the Farne...

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Autores principales: Chen, Frank, Ellis, Ewa, Strom, Stephen C, Shneider, Benjamin L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819672/
https://ncbi.nlm.nih.gov/pubmed/19809379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3181c2df16
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