Hepatocyte transplantation in bile salt export pump-deficient mice: selective growth advantage of donor hepatocytes under bile acid stress

The bile salt export pump (Bsep) mediates the hepatic excretion of bile acids, and its deficiency causes progressive familial intrahepatic cholestasis. The current study aimed to induce bile acid stress in Bsep(−/−) mice and to test the efficacy of hepatocyte transplantation in this disease model. W...

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Detalhes bibliográficos
Main Authors: Chen, Huey-Ling, Chen, Hui-Ling, Yuan, Ray-Hwang, Wu, Shang-Hsin, Chen, Ya-Hui, Chien, Chin-Sung, Chou, Shi-Ping, Wang, Renxue, Ling, Victor, Chang, Mei-Hwei
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118236/
https://ncbi.nlm.nih.gov/pubmed/22564513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2012.01586.x
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