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Hepatocyte transplantation in bile salt export pump-deficient mice: selective growth advantage of donor hepatocytes under bile acid stress
The bile salt export pump (Bsep) mediates the hepatic excretion of bile acids, and its deficiency causes progressive familial intrahepatic cholestasis. The current study aimed to induce bile acid stress in Bsep(−/−) mice and to test the efficacy of hepatocyte transplantation in this disease model. W...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BlackWell Publishing Ltd
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118236/ https://ncbi.nlm.nih.gov/pubmed/22564513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2012.01586.x |
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