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A Novel Bile Acid-Activated Vitamin D Receptor Signaling in Human Hepatocytes
Vitamin D receptor (VDR) is activated by natural ligands, 1α, 25-dihydroxy-vitamin D(3) [1α,25(OH)(2)-D(3)] and lithocholic acid (LCA). Our previous study shows that VDR is expressed in human hepatocytes, and VDR ligands inhibit bile acid synthesis and transcription of the gene encoding cholesterol...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875805/ https://ncbi.nlm.nih.gov/pubmed/20371703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0482 |
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