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Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7α-hydroxylase gene expression

Mouse fibroblast growth factor 15 (FGF15) and human ortholog FGF19 have been identified as the bile acid-induced intestinal factors that mediate bile acid feedback inhibition of cholesterol 7α-hydroxylase gene transcription in mouse liver. The mechanism underlying FGF15/FGF19 inhibition of bile acid...

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書誌詳細
主要な著者: Song, Kwang-Hoon, Li, Tiangang, Owsley, Erika, Strom, Stephen, Chiang, John Y. L.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614454/
https://ncbi.nlm.nih.gov/pubmed/19085950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22627
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