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Forkhead box transcription factor O1 inhibits cholesterol 7α-hydroxylase in human hepatocytes and in high fat diet-fed mice

The conversion of cholesterol to bile acids is the major pathway for cholesterol catabolism. Bile acids are metabolic regulators of triglycerides and glucose metabolism in the liver. This study investigated the roles of FoxO1 in the regulation of cholesterol 7α-hydroxylase (CYP7A1) gene expression i...

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Detalhes bibliográficos
Main Authors: Li, Tiangang, Ma, Huiyan, Park, Young Joo, Lee, Yoon-Kwang, Strom, Stephen, Moore, David D., Chiang, John Y. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743791/
https://ncbi.nlm.nih.gov/pubmed/19463968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.05.004
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