Forkhead box transcription factor O1 inhibits cholesterol 7α-hydroxylase in human hepatocytes and in high fat diet-fed mice

The conversion of cholesterol to bile acids is the major pathway for cholesterol catabolism. Bile acids are metabolic regulators of triglycerides and glucose metabolism in the liver. This study investigated the roles of FoxO1 in the regulation of cholesterol 7α-hydroxylase (CYP7A1) gene expression i...

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Bibliographische Detailangaben
Hauptverfasser: Li, Tiangang, Ma, Huiyan, Park, Young Joo, Lee, Yoon-Kwang, Strom, Stephen, Moore, David D., Chiang, John Y. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743791/
https://ncbi.nlm.nih.gov/pubmed/19463968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.05.004
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