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Potency of Individual Bile Acids to Regulate Bile Acid Synthesis and Transport Genes in Primary Human Hepatocyte Cultures

Bile acids (BAs) are known to regulate their own homeostasis, but the potency of individual bile acids is not known. This study examined the effects of cholic acid (CA), chenodeoxycholic acid (CDCA), deoxycholic acid (DCA), lithocholic acid (LCA) and ursodeoxycholic acid (UDCA) on expression of BA s...

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Détails bibliographiques
Publié dans:Toxicol Sci
Auteurs principaux: Liu, Jie, Lu, Hong, Lu, Yuan-Fu, Lei, Xiaohong, Cui, Julia Yue, Ellis, Ewa, Strom, Stephen C., Klaassen, Curtis D.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
114
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271050/
https://ncbi.nlm.nih.gov/pubmed/25055961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu151
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