Potency of Individual Bile Acids to Regulate Bile Acid Synthesis and Transport Genes in Primary Human Hepatocyte Cultures

Bile acids (BAs) are known to regulate their own homeostasis, but the potency of individual bile acids is not known. This study examined the effects of cholic acid (CA), chenodeoxycholic acid (CDCA), deoxycholic acid (DCA), lithocholic acid (LCA) and ursodeoxycholic acid (UDCA) on expression of BA s...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Liu, Jie, Lu, Hong, Lu, Yuan-Fu, Lei, Xiaohong, Cui, Julia Yue, Ellis, Ewa, Strom, Stephen C., Klaassen, Curtis D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
114
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271050/
https://ncbi.nlm.nih.gov/pubmed/25055961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu151
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