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The Role of Sirt1 in Bile Acid Regulation during Calorie Restriction in Mice
Sirtuin 1 (Sirt1) is an NAD(+)-dependent protein deacetylase that is proposed to mediate many health-promoting effects of calorie restriction (CR). We recently reported that short-term CR increased the bile acid (BA) pool size in mice, likely due to increased BA synthesis in liver. Given the importa...
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Pubblicato in: | PLoS One |
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Autori principali: | , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Public Library of Science
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4570809/ https://ncbi.nlm.nih.gov/pubmed/26372644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138307 |
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