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Short-term Calorie Restriction Feminizes the mRNA Profiles of Drug Metabolizing Enzymes and Transporters in Livers of Mice

Calorie restriction (CR) is one of the most effective anti-aging interventions in mammals. A modern theory suggests that aging results from a decline in detoxification capabilities and thus accumulation of damaged macromolecules. The present study aimed to determine how short-term CR alters mRNA pro...

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Publicado en:Toxicol Appl Pharmacol
Autores principales: Fu, Zidong Donna, Klaassen, Curtis D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659498/
https://ncbi.nlm.nih.gov/pubmed/24240088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.11.003
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