Levels of DNA Methylation Vary at CpG Sites across the BRCA1 Promoter, and Differ According to Triple Negative and “BRCA-Like” Status, in Both Blood and Tumour DNA

Triple negative breast cancer is typically an aggressive and difficult to treat subtype. It is often associated with loss of function of the BRCA1 gene, either through mutation, loss of heterozygosity or methylation. This study aimed to measure methylation of the BRCA1 gene promoter at individual Cp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Daniels, Sarah L., Burghel, George J., Chambers, Philip, Al-Baba, Shadi, Connley, Daniel D., Brock, Ian W., Cramp, Helen E., Dotsenko, Olena, Wilks, Octavia, Wyld, Lynda, Cross, Simon S., Cox, Angela
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963032/
https://ncbi.nlm.nih.gov/pubmed/27463681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160174
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