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Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice.

Matrix-attachment regions (MARs) may function as domain boundaries and partition chromosomes into independently regulated units. We have tested whether MAR sequences from the chicken lysozyme locus, the so-called A-elements, can confer position-independent regulation to a whey acidic protein (WAP) t...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: McKnight, R A, Shamay, A, Sankaran, L, Wall, R J, Hennighausen, L
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49621/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1495984/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.15.6943
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